An aggressive cabergoline-resistant, temozolomide-responsive macroprolactinoma due to a germline SDHB pathogenic variant in the absence of paraganglioma or pheochromocytoma

An aggressive cabergoline-resistant, temozolomide-responsive macroprolactinoma due to a germline SDHB pathogenic variant in the absence of paraganglioma or pheochromocytoma

ContextGermline succinate dehydrogenase subunit B (SDHB) pathogenic variants are characteristic of familial paraganglioma (PGL) syndrome type 4. This syndrome frequently presents with abdominal PGL and has high tendency for locally aggressive behavior and distant metastasis. The vast majority of pit...

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Bibliographic Details
Main Authors: Ali S. Alzahrani, Abdulghani Bin Nafisah, Meshael Alswailem, Yosra Moria, Dagmara Poprawski, Hindi Al-Hindi, Karel Pacak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Endocrinology
Subjects:
macroprolactinoma
SDHB
pituitary adenoma
cabergoline
temozolomide
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1273093/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1273093/full

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