Cerebrospinal fluid proteomics in recent-onset Narcolepsy type 1 reveals activation of the complement system

Cerebrospinal fluid proteomics in recent-onset Narcolepsy type 1 reveals activation of the complement system

IntroductionNarcolepsy type 1 (NT1) is a rare, chronic and disabling neurological disease causing excessive daytime sleepiness and cataplexy. NT1 is characterized pathologically by an almost complete loss of neurons producing the orexin neuropeptides in the lateral hypothalamus. Genetic and environm...

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Main Authors: Ikram Ayoub, Yves Dauvilliers, Lucie Barateau, Thaïs Vermeulen, Emmanuelle Mouton-Barbosa, Marlène Marcellin, Anne Gonzalez-de-Peredo, Catharina C. Gross, Abdelhadi Saoudi, Roland Liblau
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
narcolepsy type 1
neuroimmunology
cerebrospinal fluid
proteomics
complement system
coagulation system
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1108682/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1108682/full

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