An assessment of bioinformatics tools for the detection of human endogenous retroviral insertions in short-read genome sequencing data

An assessment of bioinformatics tools for the detection of human endogenous retroviral insertions in short-read genome sequencing data

There is a growing interest in the study of human endogenous retroviruses (HERVs) given the substantial body of evidence that implicates them in many human diseases. Although their genomic characterization presents numerous technical challenges, next-generation sequencing (NGS) has shown potential t...

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Bibliographic Details
Main Authors: Harry Bowles, Renata Kabiljo, Ahmad Al Khleifat, Ashley Jones, John P. Quinn, Richard J. B. Dobson, Chad M. Swanson, Ammar Al-Chalabi, Alfredo Iacoangeli
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Bioinformatics
Subjects:
herv-k
benchmarking
whole-genome sequencing
retrovirus
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2022.1062328/full

Internet

https://www.frontiersin.org/articles/10.3389/fbinf.2022.1062328/full

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