Herbo-mineral formulation, Divya-Swasari-Vati averts SARS-CoV-2 pseudovirus entry into human alveolar epithelial cells by interfering with spike protein-ACE 2 interaction and IL-6/TNF-α /NF-κB signaling

Herbo-mineral formulation, Divya-Swasari-Vati averts SARS-CoV-2 pseudovirus entry into human alveolar epithelial cells by interfering with spike protein-ACE 2 interaction and IL-6/TNF-α /NF-κB signaling

The herbo-mineral formulation, Divya-Swasari-Vati (DSV), is a well-known Ayurvedic medication for respiratory ailments. In a recent pre-clinical study, DSV rescued humanized zebrafish from SARS-CoV-2 S-protein-induced pathologies. This merited for an independent evaluation of DSV as a SARS-CoV-2 ent...

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Bibliographic Details
Main Authors: Acharya Balkrishna, Sudeep Goswami, Hoshiyar Singh, Vivek Gohel, Rishabh Dev, Swati Haldar, Anurag Varshney
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Divya-Swasari-Vati (DSV)
SARS-CoV-2
pseudovirus
spike protein
ACE 2
proinflammatory cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1024830/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1024830/full

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