Engineering the Signal Resolution of a Paper-Based Cell-Free Glutamine Biosensor with Genetic Engineering, Metabolic Engineering, and Process Optimization

Engineering the Signal Resolution of a Paper-Based Cell-Free Glutamine Biosensor with Genetic Engineering, Metabolic Engineering, and Process Optimization

Specialized cancer treatments have the potential to exploit glutamine dependence to increase patient survival rates. Glutamine diagnostics capable of tracking a patient’s response to treatment would enable a personalized treatment dosage to optimize the tradeoff between treatment success and dangero...

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Bibliographic Details
Main Authors: Tyler J. Free, Joseph P. Talley, Chad D. Hyer, Catherine J. Miller, Joel S. Griffitts, Bradley C. Bundy
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Sensors
Subjects:
biosensor
glutamine
cell-free protein synthesis (CFPS)
cancer
Online Access:https://www.mdpi.com/1424-8220/24/10/3073

Internet

https://www.mdpi.com/1424-8220/24/10/3073

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