Protective Effects of Statin Therapy in Cirrhosis Are Limited by a Common SLCO1B1 Transporter Variant

Protective Effects of Statin Therapy in Cirrhosis Are Limited by a Common SLCO1B1 Transporter Variant

Complications of cirrhosis and portal hypertension (PH) can be reduced by statin therapy. The common loss‐of‐function variant p.V174A in the solute carrier organic anion transporter gene 1B1 (SLCO1B1) gene encoding the organic anion transporting polypeptide 1B1 results in decreased hepatic uptake of...

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Bibliographic Details
Main Authors: Melissa Merkel, Christina Schneider, Robin Greinert, Alexander Zipprich, Cristina Ripoll, Frank Lammert, Matthias C. Reichert
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2021-10-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1753

Internet

https://doi.org/10.1002/hep4.1753

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