Protective Effects of Statin Therapy in Cirrhosis Are Limited by a Common SLCO1B1 Transporter Variant

Protective Effects of Statin Therapy in Cirrhosis Are Limited by a Common SLCO1B1 Transporter Variant

Complications of cirrhosis and portal hypertension (PH) can be reduced by statin therapy. The common loss‐of‐function variant p.V174A in the solute carrier organic anion transporter gene 1B1 (SLCO1B1) gene encoding the organic anion transporting polypeptide 1B1 results in decreased hepatic uptake of...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Melissa Merkel, Christina Schneider, Robin Greinert, Alexander Zipprich, Cristina Ripoll, Frank Lammert, Matthias C. Reichert
Format: Artikel
Sprache:English
Veröffentlicht: Wolters Kluwer Health/LWW 2021-10-01
Schriftenreihe:Hepatology Communications
Online Zugang:https://doi.org/10.1002/hep4.1753

Online

https://doi.org/10.1002/hep4.1753

Ähnliche Einträge