Neutrophil extracellular traps and heparin-induced antibodies contribute to vascular access thrombosis in hemodialysis patients

Neutrophil extracellular traps and heparin-induced antibodies contribute to vascular access thrombosis in hemodialysis patients

Background Anti-heparin/platelet factor 4 (PF4) antibodies may trigger severe thrombotic complications in hemodialysis (HD) patients. Tetrameric PF4 has a high affinity for extracellular DNA, which is a key component of neutrophil extracellular traps (NETs); therefore, the interactions between anti-...

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Bibliographic Details
Main Authors: Hoi Woul Lee, Jung Nam An, Hyung Seok Lee, Young Rim Song, Hyung Jik Kim, Sung Gyun Kim, Jwa-Kyung Kim
Format: Article
Language:English
Published: The Korean Society of Nephrology 2021-12-01
Series:Kidney Research and Clinical Practice
Subjects:
extracellular traps
platelet factor 4
renal dialysis
thrombosis
vascular access
Online Access:http://www.krcp-ksn.org/upload/pdf/j-krcp-21-080.pdf

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http://www.krcp-ksn.org/upload/pdf/j-krcp-21-080.pdf

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