Novel Phage-Derived Depolymerase with Activity against <i>Proteus mirabilis</i> Biofilms

Novel Phage-Derived Depolymerase with Activity against <i>Proteus mirabilis</i> Biofilms

The adherence of <i>Proteus mirabilis</i> to the surface of urinary catheters leads to colonization and eventual blockage of the catheter lumen by unique crystalline biofilms produced by these opportunistic pathogens, making <i>P. mirabilis</i> one of the leading causes of ca...

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Bibliographic Details
Main Authors: Cormac J. Rice, Stephen A. Kelly, Seamus C. O’Brien, Erinn M. Melaugh, Jan C. B. Ganacias, Zheng Hua Chai, Brendan F. Gilmore, Timofey Skvortsov
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Microorganisms
Subjects:
<i>Proteus</i>
bacteriophage
urinary tract infections (UTIs)
depolymerases
antibiotic resistance
pectate lyase
Online Access:https://www.mdpi.com/2076-2607/9/10/2172

Internet

https://www.mdpi.com/2076-2607/9/10/2172

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