Association study of a single nucleotide polymorphism in the hypoxia response element of the macrophage migration inhibitory factor gene promoter with suicide completers in the Japanese population

Association study of a single nucleotide polymorphism in the hypoxia response element of the macrophage migration inhibitory factor gene promoter with suicide completers in the Japanese population

Abstract Background More than 800 000 people die by suicide annually. The heritability of suicide is 30%–50%. We focused on the hypoxia response element (HRE), which promotes the expression of macrophage migration inhibitory factor (MIF) via the hypoxia‐inducible factor (HIF) pathway, important in n...

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Bibliographic Details
Main Authors: Toshiyuki Shirai, Satoshi Okazaki, Takaki Tanifuji, Ikuo Otsuka, Masao Miyachi, Shohei Okada, Ryota Shindo, Tadasu Horai, Kentaro Mouri, Motonori Takahashi, Takeshi Kondo, Yasuhiro Ueno, Akitoyo Hishimoto
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Neuropsychopharmacology Reports
Subjects:
genetics: Human
hypoxia inducible factor
macrophage migration inhibitory factor
single nucleotide polymorphism
suicide: basic/clinical
Online Access:https://doi.org/10.1002/npr2.12410

Internet

https://doi.org/10.1002/npr2.12410

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