Construction and validation of a prognostic model for gastrointestinal stromal tumors based on copy number alterations and clinicopathological characteristics

Construction and validation of a prognostic model for gastrointestinal stromal tumors based on copy number alterations and clinicopathological characteristics

BackgroundThe increasing incidence of gastrointestinal stromal tumors (GISTs) has led to the discovery of more novel prognostic markers. We aim to establish an unsupervised prognostic model for the early prediction of the prognosis of future patients with GISTs and to guide clinical treatment.Method...

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Bibliographic Details
Main Authors: Heng Zhao, Nuohan Song, Hao Feng, Qiang Lei, Yingying Zheng, Jing Liu, Chunyan Liu, Zhengbin Chai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
gastrointestinal stromal tumors
copy number alteration
t-distributed stochastic neighbor embedding
microsatellite instability
fraction genome altered
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1055174/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1055174/full

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