Biased Pol II fidelity contributes to conservation of functional domains in the Potato spindle tuber viroid genome.

Accurate calculation of mutation rates for viruses and viroids is necessary for evolutionary studies and to evaluate adaptation potential. However, estimation of in vivo mutation rates is complicated by selection, which leads to loss or proliferation of certain mutations. To minimize this concern, l...

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Bibliographic Details
Main Authors: Jian Wu, David M Bisaro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009144