Transcriptome, methylome and genomic variations analysis of ectopic thyroid glands.

BACKGROUND: Congenital hypothyroidism from thyroid dysgenesis (CHTD) is predominantly a sporadic disease characterized by defects in the differentiation, migration or growth of thyroid tissue. Of these defects, incomplete migration resulting in ectopic thyroid tissue is the most common (up to 80%)....

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Bibliographic Details
Main Authors: Rasha Abu-Khudir, Jean Paquette, Anne Lefort, Frederick Libert, Jean-Pierre Chanoine, Gilbert Vassart, Johnny Deladoëy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2955549?pdf=render