Animal HECT ubiquitin ligases: evolution and functional implications
<p>Abstract</p> <p>Background</p> <p>HECT ubiquitin ligases (HECT E3s) are key components of the eukaryotic ubiquitin-proteasome system and are involved in the genesis of several human diseases. In this study, I analyze the patterns of diversification of HECT E3s since...
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Format: | Article |
Language: | English |
Published: |
BMC
2010-02-01
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Series: | BMC Evolutionary Biology |
Online Access: | http://www.biomedcentral.com/1471-2148/10/56 |