Animal HECT ubiquitin ligases: evolution and functional implications

<p>Abstract</p> <p>Background</p> <p>HECT ubiquitin ligases (HECT E3s) are key components of the eukaryotic ubiquitin-proteasome system and are involved in the genesis of several human diseases. In this study, I analyze the patterns of diversification of HECT E3s since...

Full description

Bibliographic Details
Main Author: Marín Ignacio
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/10/56