Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis

Abstract Megakaryocytopoiesis is a complex differentiation process driven by the hormone thrombopoietin by which haematopoietic progenitor cells give rise to megakaryocytes, the giant bone marrow cells that in turn break down to form blood platelets. The Tribbles Pseudokinase 3 gene (TRIB3) encodes...

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Bibliographic Details
Main Authors: Lee Butcher, Maninder Ahluwalia, Tiit Örd, Jessica Johnston, Roger H. Morris, Endre Kiss-Toth, Tõnis Örd, Jorge D. Erusalimsky
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07096-w