Organocatalytic asymmetric bromohydroxylation of tri-substituted alkenes
This work describes an effective enantioselective bromohydroxylation of tri-substituted alkenes with (DHQD)2PHAL as catalyst and H2O as nucleophile, providing a variety of corresponding optically active bromohydrins with up to 95% ee.
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-06-01
|
| Series: | Tetrahedron Chem |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666951X23000050 |