Glu-Urea-Lys Scaffold Functionalized Superparamagnetic Iron Oxide Nanoparticles Targeting PSMA for In Vivo Molecular MRI of Prostate Cancer

Glu-Urea-Lys Scaffold Functionalized Superparamagnetic Iron Oxide Nanoparticles Targeting PSMA for In Vivo Molecular MRI of Prostate Cancer

The prostate specific membrane antigen (PSMA), extensively overexpressed on prostate cancer (PCa) cell surface, has been validated as a diagnostic biomarker for PCa. However, insufficient attention has been paid to the development of PSMA-specific probes loaded with small chemical molecules for the...

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Bibliographic Details
Main Authors: Wei Zhou, Jiandong Huang, Qingwei Xiao, Shunmin Hu, Shijia Li, Jie Zheng, Zhiyun Du, Jiangling Peng, Huixiong Chen
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
prostate cancer
PSMA
molecular imaging
MRI contrast agent
SPIONs
Online Access:https://www.mdpi.com/1999-4923/14/10/2051

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https://www.mdpi.com/1999-4923/14/10/2051

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