Innate immunity: Looking beyond T-cells in radiation and immunotherapy combinations

Radiation therapy is an established and effective anti-cancer treatment modality. Extensive pre-clinical experimentation has demonstrated that the pro-inflammatory properties of irradiation may be synergistic with checkpoint immunotherapy. Radiation induces double-stranded DNA breaks (dsDNA). Sensin...

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Bibliographic Details
Main Authors: R.A. McMahon, C. D'Souza, P.J. Neeson, S. Siva
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558623000647