Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases

Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases

Advancements in genome editing make possible to exploit the functions of enzymes for efficient DNA modifications with tremendous potential to treat human genetic diseases. Several nuclease genome editing strategies including Meganucleases (MNs), Zinc Finger Nucleases (ZFNs), Transcription Activator-...

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Bibliographic Details
Main Authors: Yaoyao Lu, Cedric Happi Mbakam, Bo Song, Eli Bendavid, Jacques-P. Tremblay
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genome Editing
Subjects:
gene editing
ZFN
TALEN
CRISPR-cas
Cytidine Base Editor (CBE)
Adenosine Base Editor (ABE)
Online Access:https://www.frontiersin.org/articles/10.3389/fgeed.2022.892769/full

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https://www.frontiersin.org/articles/10.3389/fgeed.2022.892769/full

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