Expression of HIF-1α and Genes Involved in Glucose Metabolism Is Increased in Cervical Cancer and HPV-16-Positive Cell Lines

Expression of HIF-1α and Genes Involved in Glucose Metabolism Is Increased in Cervical Cancer and HPV-16-Positive Cell Lines

Cervical cancer (CC) is the most common cancer in women in the lower genital tract. The main risk factor for developing CC is persistent infection with HPV 16. The E6 and E7 oncoproteins of HPV 16 have been related to metabolic reprogramming in cancer through the regulation of the expression and sta...

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Bibliographic Details
Main Authors: Víctor D. Priego-Hernández, Adán Arizmendi-Izazaga, Diana G. Soto-Flores, Norma Santiago-Ramón, Milagros D. Feria-Valadez, Napoleón Navarro-Tito, Hilda Jiménez-Wences, Dinorah N. Martínez-Carrillo, Eric G. Salmerón-Bárcenas, Marco A. Leyva-Vázquez, Berenice Illades-Aguiar, Luz del C. Alarcón-Romero, Julio Ortiz-Ortiz
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pathogens
Subjects:
HPV 16
HIF-1α
glucose metabolism
metabolic reprogramming
cervical cancer
Online Access:https://www.mdpi.com/2076-0817/12/1/33

Internet

https://www.mdpi.com/2076-0817/12/1/33

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