Hindlimb unloading, a physiological model of microgravity, modifies the murine bone marrow IgM repertoire in a similar manner as aging but less strongly

Hindlimb unloading, a physiological model of microgravity, modifies the murine bone marrow IgM repertoire in a similar manner as aging but less strongly

Abstract Background The spaceflight environment is an extreme environment that affects the immune system of approximately 50% of astronauts. With planned long-duration missions, such as the deployment of the Lunar Gateway and possible interplanetary missions, it is mandatory to determine how all com...

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Bibliographic Details
Main Authors: Coralie Fonte, Pauline Jacob, Anne Vanet, Stéphanie Ghislin, Jean-Pol Frippiat
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Immunity & Ageing
Subjects:
Antibody
Spaceflight
Humoral immunity
Stress
Immune system
B lymphopoiesis
Online Access:https://doi.org/10.1186/s12979-023-00393-1

Internet

https://doi.org/10.1186/s12979-023-00393-1

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