EZH2/H3K27Me3 and phosphorylated EZH2 predict chemotherapy response and prognosis in ovarian cancer

Background EZH2 acts as an oncogene through canonical pathway EZH2/H3K27Me3 and uncanonical pathway pAkt1/pS21EZH2 in many solid tumors including ovarian cancer. However, the clinical value of EZH2/H3K27Me3 and pAkt1/pS21EZH2 remain unclear. In the current study, we aim to investigate the correlatio...

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Bibliographic Details
Main Authors: Si Sun, Qiang Yang, E Cai, Bangxing Huang, Feiquan Ying, Yiping Wen, Jing Cai, Ping Yang
Format: Article
Language:English
Published: PeerJ Inc. 2020-05-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/9052.pdf