A new effective antiplasmodial compound: Nanoformulated pyrimethamine

A new effective antiplasmodial compound: Nanoformulated pyrimethamine

Objectives: The aim of this study was to evaluate the efficacy of pyrimethamine-loaded poloxamer 407 nanomicelles on Plasmodium berghei strain NICD in vivo. Methods: Pyrimethamine-loaded nanomicelles were prepared and their zeta potential, particle size and polydispersity index were measured. For an...

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Bibliographic Details
Main Authors: Nader Pestehchian, Mohammad Reza Vafaei, Pardis Nematolahy, Jaleh Varshosaz, Hossein Ali Yousefi, Vahab Ziaei Bide, Hamed Kalani
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Nanomicelles
Plasmodium berghei
Malaria
Poloxamer 407
Pyrimethamine
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716519302000

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http://www.sciencedirect.com/science/article/pii/S2213716519302000

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