Catalytic asymmetric dearomatization of phenols via divergent intermolecular (3 + 2) and alkylation reactions

Abstract The catalytic asymmetric dearomatization (CADA) reaction has proved to be a powerful protocol for rapid assembly of valuable three-dimensional cyclic compounds from readily available planar aromatics. In contrast to the well-studied indoles and naphthols, phenols have been considered challe...

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Bibliographic Details
Main Authors: Xiang Gao, Tian-Jiao Han, Bei-Bei Li, Xiao-Xiao Hou, Yuan-Zhao Hua, Shi-Kun Jia, Xiao Xiao, Min-Can Wang, Donghui Wei, Guang-Jian Mei
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40891-w