Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy
SUMMARY CENP-F is a large multifunctional protein with demonstrated regulatory roles in cell proliferation, vesicular transport and cell shape through its association with the microtubule (MT) network. Until now, analysis of CENP-F has been limited to in vitro analysis. Here, using a Cre-loxP system...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-07-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/5/4/468 |