Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy

SUMMARY CENP-F is a large multifunctional protein with demonstrated regulatory roles in cell proliferation, vesicular transport and cell shape through its association with the microtubule (MT) network. Until now, analysis of CENP-F has been limited to in vitro analysis. Here, using a Cre-loxP system...

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Bibliographic Details
Main Authors: Ellen Dees, Paul M. Miller, Katherine L. Moynihan, Ryan D. Pooley, R. Pierre Hunt, Cristi L. Galindo, Jeffrey N. Rottman, David M. Bader
Format: Article
Language:English
Published: The Company of Biologists 2012-07-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/5/4/468