hoDCA: higher order direct-coupling analysis
Abstract Background Direct-coupling analysis (DCA) is a method for protein contact prediction from sequence information alone. Its underlying principle is parameter estimation for a Hamiltonian interaction function stemming from a maximum entropy model with one- and two-point interactions. Vastly gr...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-12-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2583-6 |