Tac2-N acts as a novel oncogene and promotes tumor metastasis via activation of NF-κB signaling in lung cancer

Abstract Background High rates of recurrence and metastasis are the major cause of the poor outcomes for patients with lung cancer. In previous research, we have demonstrated that Tac2-N promotes tumor growth by suppressing p53 signaling in lung cancer. Beyond that, other biological functions and cl...

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Bibliographic Details
Main Authors: Xianglin Hao, Li-yun Gao, Ning Zhang, Hongqiang Chen, Xiao Jiang, Wenbin Liu, Lin Ao, Jia Cao, Fei Han, Jinyi Liu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-019-1316-7