Chronic effects of blast injury on the microvasculature in a transgenic mouse model of Alzheimer’s disease related Aβ amyloidosis

Chronic effects of blast injury on the microvasculature in a transgenic mouse model of Alzheimer’s disease related Aβ amyloidosis

Abstract Background Altered cerebrovascular function and accumulation of amyloid-β (Aβ) after traumatic brain injury (TBI) can contribute to chronic neuropathology and increase the risk for Alzheimer’s disease (AD). TBI due to a blast-induced shock wave (bTBI) adversely affects the neurovascular uni...

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Bibliographic Details
Main Authors: Alexander T. Clark, Eric E. Abrahamson, Matthew M. Harper, Milos D. Ikonomovic
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Fluids and Barriers of the CNS
Subjects:
Alzheimer’s disease
Amyloid
Astrocyte
Blast injury
Blood–brain barrier
NVU
Online Access:https://doi.org/10.1186/s12987-021-00301-z

Internet

https://doi.org/10.1186/s12987-021-00301-z

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