Deciphering COVID-19 host transcriptomic complexity and variations for therapeutic discovery against new variants

Summary: The molecular manifestations of host cells responding to SARS-CoV-2 and its evolving variants of infection are vastly different across the studied models and conditions, imposing challenges for host-based antiviral drug discovery. Based on the postulation that antiviral drugs tend to revers...

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Bibliographic Details
Main Authors: Jing Xing, Rama Shankar, Meehyun Ko, Keke Zhang, Sulin Zhang, Aleksandra Drelich, Shreya Paithankar, Eugene Chekalin, Mei-Sze Chua, Surender Rajasekaran, Chien-Te Kent Tseng, Mingyue Zheng, Seungtaek Kim, Bin Chen
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222013402