Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment

The tumor microenvironment is crucial for the growth of cancer cells, triggering particular biochemical and physiological changes, which frequently influence the outcome of anticancer therapies. The biochemical rationale behind many of these phenomena resides in the activation of transcription facto...

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Bibliographic Details
Main Authors: Andrea Angeli, Fabrizio Carta, Alessio Nocentini, Jean-Yves Winum, Raivis Zalubovskis, Atilla Akdemir, Valentina Onnis, Wagdy M. Eldehna, Clemente Capasso, Giuseppina De Simone, Simona Maria Monti, Simone Carradori, William A. Donald, Shoukat Dedhar, Claudiu T. Supuran
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Metabolites
Subjects:
carbonic anhydrase
hypoxia
pH regulation
inhibitor
sulfonamide
SLC-0111
Online Access:https://www.mdpi.com/2218-1989/10/10/412

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https://www.mdpi.com/2218-1989/10/10/412

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