Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice

Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice

Abstract Background HMG-CoA reductase inhibitors (statins) are cholesterol-lowering drugs widely used to treat hypercholesterolemia and prevent cardiovascular disease. Statins are generally well tolerated, but adverse reactions may occur, particularly myopathy and new onset of diabetes. The exact me...

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Váldodahkkit: Estela Lorza-Gil, Marta García-Arevalo, Bianca Cristine Favero, Maria Cristina C. Gomes-Marcondes, Helena C. F. Oliveira
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: BMC 2019-08-01
Ráidu:Journal of Translational Medicine
Fáttát:
Statins
Insulin resistance
Muscle proteolysis
Myotoxicity
Liŋkkat:http://link.springer.com/article/10.1186/s12967-019-2045-6

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http://link.springer.com/article/10.1186/s12967-019-2045-6

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