A Notch-mediated, temporal asymmetry in BMP pathway activation promotes photoreceptor subtype diversification.
Neural progenitors produce neurons whose identities can vary as a function of the time that specification occurs. Here, we describe the heterochronic specification of two photoreceptor (PhR) subtypes in the zebrafish pineal gland. We find that accelerating PhR specification by impairing Notch signal...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.2006250 |