Lower diurnal HPA-axis activity in male hypertensive and coronary heart disease patients predicts future CHD risk

Lower diurnal HPA-axis activity in male hypertensive and coronary heart disease patients predicts future CHD risk

BackgroundCoronary heart disease (CHD) and its major risk factor hypertension have both been associated with altered activity of the hypothalamus-pituitary-adrenal (HPA)-axis but the biological mechanisms underlying prospective associations with adverse disease outcomes are unclear. We investigated...

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Bibliographic Details
Main Authors: Cathy Degroote, Roland von Känel, Livia Thomas, Claudia Zuccarella-Hackl, Nadine Messerli-Bürgy, Hugo Saner, Roland Wiest, Petra H. Wirtz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Endocrinology
Subjects:
HPA-axis
cortisol
coronary heart disease
hypertension
coagulation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1080938/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1080938/full

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