<i>UNC5C</i>: Novel Gene Associated with Psychiatric Disorders Impacts Dysregulation of Axon Guidance Pathways

<i>UNC5C</i>: Novel Gene Associated with Psychiatric Disorders Impacts Dysregulation of Axon Guidance Pathways

The UNC-5 family of netrin receptor genes, predominantly expressed in brain tissues, plays a pivotal role in various neuronal processes. Mutations in genes involved in axon development contribute to a wide spectrum of human diseases, including developmental, neuropsychiatric, and neurodegenerative d...

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Bibliographic Details
Main Authors: Simone Treccarichi, Pinella Failla, Mirella Vinci, Antonino Musumeci, Angelo Gloria, Anna Vasta, Giuseppe Calabrese, Carla Papa, Concetta Federico, Salvatore Saccone, Francesco Calì
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Genes
Subjects:
<i>UNC5C</i> gene
netrin 1/DCC
axon guidance
microtubule dynamics
whole-exome sequencing
Online Access:https://www.mdpi.com/2073-4425/15/3/306

Internet

https://www.mdpi.com/2073-4425/15/3/306

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