Circ_0002984 promotes proliferation, migration and inflammatory cytokine secretion and inhibits apoptosis of rheumatoid arthritis fibroblast-like synoviocytes by inducing PCSK6 through miR-543

Circ_0002984 promotes proliferation, migration and inflammatory cytokine secretion and inhibits apoptosis of rheumatoid arthritis fibroblast-like synoviocytes by inducing PCSK6 through miR-543

Abstract Background Rheumatoid arthritis (RA) is inflammatory arthritic disease, and circular RNA is involved in RA development. The aim of the present work is to analyze the role of circ_0002984 in the process of RA fibroblast-like synoviocytes (RAFLSs) and the underlying mechanism. Methods Circ_00...

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Bibliographic Details
Main Authors: Jian-zuo Lu, Jie Yang, Sheng-tuo Zhou, Kai-luo Xie
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Rheumatoid arthritis
Circ_0002984
MiR-543
PCSK6
Rheumatoid arthritis fibroblast-like synoviocytes
Online Access:https://doi.org/10.1186/s13018-023-03823-4

Internet

https://doi.org/10.1186/s13018-023-03823-4

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