Granulin as an important immune molecule involved in lamprey tissue repair and regeneration by promoting cell proliferation and migration

Abstract Progranulin (PGRN) is an autocrine growth factor that regulates cell proliferation, migration, wound healing, and tissue repair in mammals. Lamprey is the most primitive of the extant vertebrates and is regarded as the survivor of a once flourishing group of paleozoic vertebrates, with a hi...

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Bibliographic Details
Main Authors: Ruixiang Sun, Dong Wang, Yuxuan Song, Qingwei Li, Peng Su, Yue Pang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-022-00360-6