Cell-Type Specific Changes in Glial Morphology and Glucocorticoid Expression During Stress and Aging in the Medial Prefrontal Cortex

Cell-Type Specific Changes in Glial Morphology and Glucocorticoid Expression During Stress and Aging in the Medial Prefrontal Cortex

Repeated exposure to stressors is known to produce large-scale remodeling of neurons within the prefrontal cortex (PFC). Recent work suggests stress-related forms of structural plasticity can interact with aging to drive distinct patterns of pyramidal cell morphological changes. However, little is k...

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Bibliographic Details
Main Authors: Thomas E. Chan, Yael S. Grossman, Erik B. Bloss, William G. Janssen, Wendy Lou, Bruce S. McEwen, Dani Dumitriu, John H. Morrison
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
microglia
glia
glucocorticoids
prefrontal cortex
aging
chronic stress
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00146/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2018.00146/full

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