Modified combination of anti-thymocyte globulin (ATG) and post-transplant cyclophosphamide (PTCy) as compared with standard ATG protocol in haploidentical peripheral blood stem cell transplantation for acute leukemia

Modified combination of anti-thymocyte globulin (ATG) and post-transplant cyclophosphamide (PTCy) as compared with standard ATG protocol in haploidentical peripheral blood stem cell transplantation for acute leukemia

In haploidentical peripheral blood stem cell transplantation (haplo-PBSCT), the combination of anti-thymocyte globulin and post-transplant cyclophosphamide (ATG/PTCy) has a synergistic impact in preventing graft-versus-host disease (GvHD). However, little is known about the long-term consequences of...

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Bibliographic Details
Main Authors: Maryam Barkhordar, Amir Kasaeian, Ghasem Janbabai, Hossein Kamranzadeh Fumani, Sahar Tavakoli, Amir Abbas Rashidi, Seied Asadollah Mousavi, Ardeshir Ghavamzadeh, Mohammad Vaezi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
haploidentical stem cell transplantation (HSCT)
peripheral blood stem cells (PBSCs)
anti-thymocyte globulin (ATG)
post-transplantation cyclophosphamide (PTCy)
acute leukemia (AL)
Graft versus host disease (GvHD)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.921293/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.921293/full

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