Identifying key genes related to the peritubular capillary rarefaction in renal interstitial fibrosis by bioinformatics

Abstract Renal interstitial fibrosis (RIF) is a key feature of progressive chronic kidney disease (CKD), characterized by tubular epithelial cell (TEC) hypoxia and peritubular capillary (PTC) rarefaction. However, the mechanisms underlying these processes remain poorly understood. To address this kn...

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Bibliographic Details
Main Authors: Yu Zhang, Chuanbing Shi, Yiqiong Yang, Xiuxiu Hu, Haifeng Ni, Li Li, Zhengyuan Cheng, Jing Huang, Pingsheng Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46934-y