Chemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (<i>Plinia jabuticaba</i>) Wine and Derived Extracts
The alcoholic fermentation of jabuticaba berries (<i>Plinia</i> spp.) originates from a beverage with an intense taste and aroma, popularly known as jabuticaba wine (JW). In addition, polyphenols transferred from fruit peels to the final product turn this beverage into a promising source...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Jezik: | English |
| Izdano: |
MDPI AG
2023-02-01
|
| Serija: | Fermentation |
| Teme: | |
| Online dostop: | https://www.mdpi.com/2311-5637/9/2/157 |
| _version_ | 1827757528414420992 |
|---|---|
| author | Raissa Lima Marcos Vinicius T. Silva Brendo A. Gomes Ellis Helena B. C. Macedo Michele N. Santana Ana Claudia F. Amaral Jefferson R. A. Silva Pollyane G. Corrêa Ronoel Luiz O. Godoy Manuela Cristina P. A. Santiago Suzana G. Leitão Rosineide C. Simas Carla S. Carneiro Igor A. Rodrigues |
| author_facet | Raissa Lima Marcos Vinicius T. Silva Brendo A. Gomes Ellis Helena B. C. Macedo Michele N. Santana Ana Claudia F. Amaral Jefferson R. A. Silva Pollyane G. Corrêa Ronoel Luiz O. Godoy Manuela Cristina P. A. Santiago Suzana G. Leitão Rosineide C. Simas Carla S. Carneiro Igor A. Rodrigues |
| author_sort | Raissa Lima |
| collection | DOAJ |
| description | The alcoholic fermentation of jabuticaba berries (<i>Plinia</i> spp.) originates from a beverage with an intense taste and aroma, popularly known as jabuticaba wine (JW). In addition, polyphenols transferred from fruit peels to the final product turn this beverage into a promising source of bioactive agents. Here, the chemical profile and antioxidant potential of artisanal JW and derivative extracts were determined. Volatile organic compounds were determined by HS-SPME/GC-MS analysis. The wine was dried by lyophilization and subjected to liquid-liquid partitioning (water: ethyl acetate), resulting in three fractions (JWF1-3). ABTS<sup>•+</sup> and DPPH<sup>•+</sup> scavenging assays were performed to evaluate the antioxidant capacity. In addition, the extracts’ hematoprotective activity was evaluated against oxidative stress. Finally, the extracts were analyzed by LC-HRMS/MS. HS-SPME/GC-MS analysis highlighted 1,8-cineole as the main compound that contributes to the camphor/mint flavor. JWF2 and JWF3 displayed the highest antioxidant capacity. JWF2 stood out for preventing oxidative damage in red blood cells at 7.8 µg·mL<sup>−1</sup> The maximal protection of ascorbic acid occurred at 8.8 µg·mL<sup>−1</sup>. The LC-HRMS/MS analysis allowed the annotation of seventeen compounds, most of them with recognized antioxidant activity such as anthocyanins, catechins, flavanols, and phenolic acids. The results presented herein reinforce JW as a pleasant beverage with bioactive potential. |
| first_indexed | 2024-03-11T08:50:46Z |
| format | Article |
| id | doaj.art-54a52ec5d7f5424bb755a735bb8c634d |
| institution | Directory Open Access Journal |
| issn | 2311-5637 |
| language | English |
| last_indexed | 2024-03-11T08:50:46Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Fermentation |
| spelling | doaj.art-54a52ec5d7f5424bb755a735bb8c634d2023-11-16T20:26:16ZengMDPI AGFermentation2311-56372023-02-019215710.3390/fermentation9020157Chemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (<i>Plinia jabuticaba</i>) Wine and Derived ExtractsRaissa Lima0Marcos Vinicius T. Silva1Brendo A. Gomes2Ellis Helena B. C. Macedo3Michele N. Santana4Ana Claudia F. Amaral5Jefferson R. A. Silva6Pollyane G. Corrêa7Ronoel Luiz O. Godoy8Manuela Cristina P. A. Santiago9Suzana G. Leitão10Rosineide C. Simas11Carla S. Carneiro12Igor A. Rodrigues13Programa de Pós-graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, BrazilPrograma de Pós-graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, BrazilPrograma de Pós-graduação em Biotecnologia Vegetal, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, BrazilPrograma de Pós-graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, BrazilDepartamento de Produtos Naturais e Alimentos, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, BrazilLaboratório de Plantas Medicinais e Derivados, Farmanguinhos Fiocruz, Manguinhos, Rio de Janeiro 21041-250, RJ, BrazilDepartamento de Química, Universidade Federal do Amazonas, Japiim, Manaus 69077-000, AM, BrazilDepartamento de Química, Universidade Federal do Amazonas, Japiim, Manaus 69077-000, AM, BrazilEmbrapa Agroindústria de Alimentos, Rio de Janeiro 23020-470, RJ, BrazilEmbrapa Agroindústria de Alimentos, Rio de Janeiro 23020-470, RJ, BrazilPrograma de Pós-graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, BrazilLaboratório de Cromatografia e Espectrometria de Massas (LaCEM), Universidade Federal de Goiás, Goiânia 74690-900, GO, BrazilDepartamento de Produtos Naturais e Alimentos, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, BrazilPrograma de Pós-graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, BrazilThe alcoholic fermentation of jabuticaba berries (<i>Plinia</i> spp.) originates from a beverage with an intense taste and aroma, popularly known as jabuticaba wine (JW). In addition, polyphenols transferred from fruit peels to the final product turn this beverage into a promising source of bioactive agents. Here, the chemical profile and antioxidant potential of artisanal JW and derivative extracts were determined. Volatile organic compounds were determined by HS-SPME/GC-MS analysis. The wine was dried by lyophilization and subjected to liquid-liquid partitioning (water: ethyl acetate), resulting in three fractions (JWF1-3). ABTS<sup>•+</sup> and DPPH<sup>•+</sup> scavenging assays were performed to evaluate the antioxidant capacity. In addition, the extracts’ hematoprotective activity was evaluated against oxidative stress. Finally, the extracts were analyzed by LC-HRMS/MS. HS-SPME/GC-MS analysis highlighted 1,8-cineole as the main compound that contributes to the camphor/mint flavor. JWF2 and JWF3 displayed the highest antioxidant capacity. JWF2 stood out for preventing oxidative damage in red blood cells at 7.8 µg·mL<sup>−1</sup> The maximal protection of ascorbic acid occurred at 8.8 µg·mL<sup>−1</sup>. The LC-HRMS/MS analysis allowed the annotation of seventeen compounds, most of them with recognized antioxidant activity such as anthocyanins, catechins, flavanols, and phenolic acids. The results presented herein reinforce JW as a pleasant beverage with bioactive potential.https://www.mdpi.com/2311-5637/9/2/157fermentationpolyphenolsvolatile organic compoundshematoprotectionoxidative stress |
| spellingShingle | Raissa Lima Marcos Vinicius T. Silva Brendo A. Gomes Ellis Helena B. C. Macedo Michele N. Santana Ana Claudia F. Amaral Jefferson R. A. Silva Pollyane G. Corrêa Ronoel Luiz O. Godoy Manuela Cristina P. A. Santiago Suzana G. Leitão Rosineide C. Simas Carla S. Carneiro Igor A. Rodrigues Chemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (<i>Plinia jabuticaba</i>) Wine and Derived Extracts Fermentation fermentation polyphenols volatile organic compounds hematoprotection oxidative stress |
| title | Chemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (<i>Plinia jabuticaba</i>) Wine and Derived Extracts |
| title_full | Chemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (<i>Plinia jabuticaba</i>) Wine and Derived Extracts |
| title_fullStr | Chemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (<i>Plinia jabuticaba</i>) Wine and Derived Extracts |
| title_full_unstemmed | Chemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (<i>Plinia jabuticaba</i>) Wine and Derived Extracts |
| title_short | Chemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (<i>Plinia jabuticaba</i>) Wine and Derived Extracts |
| title_sort | chemical profile and hematoprotective activity of artisanal jabuticaba i plinia jabuticaba i wine and derived extracts |
| topic | fermentation polyphenols volatile organic compounds hematoprotection oxidative stress |
| url | https://www.mdpi.com/2311-5637/9/2/157 |
| work_keys_str_mv | AT raissalima chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT marcosviniciustsilva chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT brendoagomes chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT ellishelenabcmacedo chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT michelensantana chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT anaclaudiafamaral chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT jeffersonrasilva chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT pollyanegcorrea chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT ronoelluizogodoy chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT manuelacristinapasantiago chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT suzanagleitao chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT rosineidecsimas chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT carlascarneiro chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts AT igorarodrigues chemicalprofileandhematoprotectiveactivityofartisanaljabuticabaipliniajabuticabaiwineandderivedextracts |