Galectin-3 Mediates NETosis and Acts as an Autoantigen in Systemic Lupus Erythematosus-Associated Diffuse Alveolar Haemorrhage

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with enhanced NETosis and impaired degradation of neutrophil extracellular traps (NETs). Galectin-3 is a β-galactoside binding protein and is associated with neutrophil functions as well as involved in mediating autoimmune disorders...

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Bibliographic Details
Main Authors: Shih-Yao Chen, Chung-Teng Wang, Ching-Yi Chen, Pin-Yu Kuo, Chrong-Reen Wang, Ai-Li Shiau, Cheng-Hsi Chang, Chao-Liang Wu
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/11/9493