Investigation of Nanosized Crystalline Form to Improve the Oral Bioavailability of Poorly Water Soluble Cilostazol

Purpose: The aim of this study was to develop cilostazol (CLT) nanocrystals intended to improve its dissolution rate and enhance its bioavailability. Methods: In this study, CLT nanosuspension was prepared by the anti-solvent and high-pressure homogenization method. The effects of the production par...

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Bibliographic Details
Main Authors: Xiaoqing Miao, Changshan Sun, Tongying Jiang, Li Zheng, Tianyi Wang, Siling Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-05-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/9736