Participation of ATP-sensitive K+ channels in the peripheral antinociceptive effect of fentanyl in rats

Participation of ATP-sensitive K+ channels in the peripheral antinociceptive effect of fentanyl in rats

We examined the effect of several K+ channel blockers such as glibenclamide, tolbutamide, charybdotoxin (ChTX), apamin, tetraethylammonium chloride (TEA), 4-aminopyridine (4-AP), and cesium on the ability of fentanyl, a clinically used selective µ-opioid receptor agonist, to promote peripheral antin...

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Bibliographic Details
Main Authors:	A.R.A. Rodrigues, M.S.A. Castro, J.N. Francischi, A.C. Perez, I.D.G. Duarte
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2005-01-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Peripheral antinociception Fentanyl K+ channel µ-Opioid receptor agonist Glibenclamide
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000100014

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