The Lymphatic Endothelial Cell Secretome Inhibits Osteoblast Differentiation and Bone Formation

The Lymphatic Endothelial Cell Secretome Inhibits Osteoblast Differentiation and Bone Formation

Complex lymphatic anomalies (CLAs) are a set of rare diseases with unique osteopathic profiles. Recent efforts have identified how lymphatic-specific somatic activating mutations can induce abnormal lymphatic formations that are capable of invading bone and inducing bone resorption. The abnormal bon...

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Bibliographic Details
Main Authors: Ernesto Solorzano, Andrew L. Alejo, Hope C. Ball, Gabrielle T. Robinson, Andrea L. Solorzano, Rama Safadi, Jacob Douglas, Michael Kelly, Fayez F. Safadi
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cells
Subjects:
complex lymphatic anomaly
osteoblast
lymphatic endothelial cell
conditioned medium
bone
Gorham–Stout disease
Online Access:https://www.mdpi.com/2073-4409/12/20/2482

Internet

https://www.mdpi.com/2073-4409/12/20/2482

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