Melatonin-encapsuled silk fibroin electrospun nanofibers promote vascularized bone regeneration through regulation of osteogenesis-angiogenesis coupling

The repair of critical-sized bone defects poses a significant challenge due to the absence of periosteum, which plays a crucial role in coordinating the processes of osteogenesis and vascularization during bone healing. Herein, we hypothesized that melatonin-encapsuled silk Fibronin electrospun nano...

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Bibliographic Details
Main Authors: Lei Deng, Mingzhuang Hou, Nanning Lv, Quan Zhou, Xi Hua, Xiayu Hu, Xiaoyang Ge, Xuesong Zhu, Yong Xu, Huilin Yang, Xi Chen, Hao Liu, Fan He
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424000449