One-Step Pharmaceutical Preparation of PEG-Modified Exosomes Encapsulating Anti-Cancer Drugs by a High-Pressure Homogenization Technique

One-Step Pharmaceutical Preparation of PEG-Modified Exosomes Encapsulating Anti-Cancer Drugs by a High-Pressure Homogenization Technique

The use of exosomes encapsulating therapeutic agents for the treatment of diseases is of increasing interest. However, some concerns such as limited efficiency and scalability of conventional drug encapsulation methods to exosomes have still remained; thus, a new approach that enables encapsulation...

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Bibliographic Details
Main Authors: Tatsuya Fukuta, Mayumi Ikeda-Imafuku, Satoshi Kodama, Junko Kuse, Ko Matsui, Yasunori Iwao
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceuticals
Subjects:
extracellular vesicles
exosomes
high-pressure homogenization
microfluidizer
DDS
anti-cancer drugs
Online Access:https://www.mdpi.com/1424-8247/16/1/108

Internet

https://www.mdpi.com/1424-8247/16/1/108

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