The EBV-Encoded Oncoprotein, LMP1, Recruits and Transforms Fibroblasts via an ERK-MAPK-Dependent Mechanism

Latent membrane protein 1 (LMP1), the major oncoprotein encoded by Epstein–Barr virus (EBV), is expressed at widely variable levels in undifferentiated nasopharyngeal carcinoma (NPC) biopsies, fueling intense debate in the field as to the importance of this oncogenic protein in disease pathogenesis....

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Detalles Bibliográficos
Main Authors: Alexandra M Davis, Abigail Rapley, Christopher W Dawson, Lawrence S Young, Mhairi A Morris
Formato: Artigo
Idioma:English
Publicado: MDPI AG 2021-08-01
Series:Pathogens
Subjects:
Acceso en liña:https://www.mdpi.com/2076-0817/10/8/982