Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity study

Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity study

Abstract Background Metagenomic sequencing of respiratory microbial communities for pathogen identification in pneumonia may help overcome the limitations of culture-based methods. We examined the feasibility and clinical validity of rapid-turnaround metagenomics with Nanopore™ sequencing of clinica...

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Main Authors: Libing Yang, Ghady Haidar, Haris Zia, Rachel Nettles, Shulin Qin, Xiaohong Wang, Faraaz Shah, Sarah F. Rapport, Themoula Charalampous, Barbara Methé, Adam Fitch, Alison Morris, Bryan J. McVerry, Justin O’Grady, Georgios D. Kitsios
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Respiratory Research
Subjects:
Nanopore
Metagenomics sequencing
Pneumonia
Pathogen detection
Mechanical ventilation
Online Access:http://link.springer.com/article/10.1186/s12931-019-1218-4

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http://link.springer.com/article/10.1186/s12931-019-1218-4

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