CSF Markers of Oxidative Stress Are Associated with Brain Atrophy and Iron Accumulation in a 2-Year Longitudinal Cohort of Early MS

CSF Markers of Oxidative Stress Are Associated with Brain Atrophy and Iron Accumulation in a 2-Year Longitudinal Cohort of Early MS

In this prospective longitudinal study, we quantified regional brain volume and susceptibility changes during the first two years after the diagnosis of multiple sclerosis (MS) and identified their association with cerebrospinal fluid (CSF) markers at baseline. Seventy patients underwent MRI (T1 and...

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Bibliographic Details
Main Authors: Andrea Burgetova, Petr Dusek, Tomas Uher, Manuela Vaneckova, Martin Vejrazka, Romana Burgetova, Dana Horakova, Barbora Srpova, Marta Kalousova, Libuse Noskova, Katerina Levova, Jan Krasensky, Lukas Lambert
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
magnetic resonance imaging
cerebrospinal fluid
oxidative stress
iron
susceptibility
Online Access:https://www.mdpi.com/1422-0067/24/12/10048

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https://www.mdpi.com/1422-0067/24/12/10048

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