Protein thermal sensing regulates physiological amyloid aggregation

Abstract To survive, cells must respond to changing environmental conditions. One way that eukaryotic cells react to harsh stimuli is by forming physiological, RNA-seeded subnuclear condensates, termed amyloid bodies (A-bodies). The molecular constituents of A-bodies induced by different stressors v...

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Bibliographic Details
Main Authors: Dane Marijan, Evgenia A. Momchilova, Daniel Burns, Sahil Chandhok, Richard Zapf, Holger Wille, Davit A. Potoyan, Timothy E. Audas
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45536-0