Longterm Increased S100B Enhances Hippocampal Progenitor Cell Proliferation in a Transgenic Mouse Model

Longterm Increased S100B Enhances Hippocampal Progenitor Cell Proliferation in a Transgenic Mouse Model

(1) The neurotrophic protein S100B is a marker of brain injury and has been associated with neuroregeneration. In S100Btg mice rendering 12 copies of the murine S100B gene we evaluated whether S100B may serve as a treatment option. (2) In juvenile, adult, and one-year-old S100Btg mice (female and ma...

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Bibliographic Details
Main Authors: Leticia Rodrigues, Krista Minéia Wartchow, Michael Buchfelder, Diogo Onofre Souza, Carlos-Alberto Gonçalves, Andrea Kleindienst
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
S100B protein
transgenic animals
brain injury
regenerative medicine
hippocampus
adult neurogenesis
Online Access:https://www.mdpi.com/1422-0067/23/17/9600

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https://www.mdpi.com/1422-0067/23/17/9600

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